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Great read also I just joined im14andthisisdeep

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Ha 😂 it can be pretty funny, but I probably prefer /r/programmerhumor, https://preview.redd.it/arqzi89s0q9a1.jpg?auto=webp&s=c08da91b56fe36312136f5ff3fb0e2c84cee770b

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Ha 😂 it can be pretty funny, but I probably prefer /r/programmerhumor, https://preview.redd.it/arqzi89s0q9a1.jpg?auto=webp&s=c08da91b56fe36312136f5ff3fb0e2c84cee770b

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Man I love that image. Ok now i’m off to actually read

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Oct 29Liked by Nicholas Kircher

"Merely trying to do the right thing by those suffering from a most awful and deadly disease made you a target for violence."

Fear of death literally drives people crazy. Poor Tony Fauci, whose work on AIDS and COVID and other infectious disease has saved countess lives, has been vilified and threatened with violence. Many public health professionals are leavjng their posts and won't be there for the next epidemic.

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author

Amen sir. I'm so glad you said it, this is exactly what I was getting at, too. Fauci was doing the best he could within the absurdity of that Trump administration, and he was turned into a pariah. Book stores keep pushing that trash pile JFK Jr screed against him on me under the "medical science" sections and all I can do is grimace. It's history, playing out to the same tune, where it's the liars and crooks who point at honest hard-working individuals and scream "look, over there! Git 'em!", and they're given every platform.

It's a complete disgrace.

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Wow what a great read!

The study about correlation between COVID vaccines and anxiety is super interesting. I wonder if it's because people getting vaccinated were more likely to believe in COVID and therefore be anxious about it. No idea how the lack of vaccines correlated with schizophrenia though.

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Yeah! So the paper does go into detail theorising about why there might be a biochemical connection there, to quote from one of my Zotero highlights in my copy:

“We found that schizophrenia-related genes share the enrichment pathway for bile acid metabolism. Bile acids prevent the binding of spike protein with angiotensin-converting enzyme II (ACE2) and modulate the expression of ACE2, suggesting the protective role [42]."

So the protective action might be related to bile-acid metabolism!

And then on depression: "For depression, as an increased risk after COVID-19 vaccination, the results were shown for the deep interaction of spike protein-related factors such as NLRP3 inflammasome [40]. This supports that the presence of the spike protein plays a crucial role in the manifestation of diseases after COVID-19 vaccination.” (Kim et al., 2024, p. 7)

So the spike protein alone, and the simple act of of binding to ACE2 receptors, could be triggering all kinds of funky biochemical processes in certain types of cell. This could be part of the disease-causing mechanism in the Sars-CoV-2 virus itself, and possibly other respiratory pathogens of which several also use ACE2.

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